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Synchronization of autonomic control loops of blood circulation in patients with COVID-19 Full article

Journal Russian Open Medical Journal
, E-ISSN: 2304-3415
Output data Year: 2021, Volume: 10, Number: 3, DOI: 10.15275/rusomj.2021.0307
Tags autonomic control, heart rate variability, photoplethysmogram, phase synchronization, low-frequency oscillations, COVID-19
Authors Skazkina V.V. 1,2 , Krasikova N.S. 3 , Borovkova E.I. 1,3,4 , Ishbulatov Y.M. 1,3 , Gorshkov A.Yu. 5 , Korolev A.I. 5 , Dadaeva V.A. 5 , Fedorovich A.A. 5,6 , Kuligin A.V. 3 , Drapkina O.M. 5 , Karavaev A.S. 1,3,4 , Kiselev A.R. 1,3,5
Affiliations
1 Saratov State University, Saratov, Russia
2 Lappeenranta University of Technology, Finland
3 Saratov State Medical University, Saratov, Russia
4 Saratov Branch of the Institute of RadioEngineering and Electronics of Russian Academy of Sciences, Saratov, Russia
5 National Medical Research Center for Therapy and Preventive Medicine, Moscow, Russia
6 Research Center – Institute of Biomedical Problems of the Russian Academy of Sciences (IBMP), Moscow, Russia

Abstract: This study aims to investigate the strength of synchronization between the autonomic control loops of the cardiovascular system (CVS) in patients with COronaVIrus Disease 2019 (COVID-19). Methods — We calculated the total percent of phase synchronization index (S index) between the loops of autonomic control of heart rate and vascular tone in two sample groups: healthy individuals and COVID-19 patients. Results — The group-average value of the S index in COVID-19 patients is lower comparing to healthy individuals, the Mann-Whitney U-test confirmed that the differences are statistically significant. Conclusion — Obtained results suggest that the decreased value of the S index reflects the presence of a viral disease, and the S index is a promising basis for non-invasive screening diagnostics of viral diseases, particularly of COVID-19.
Cite: Skazkina V.V. , Krasikova N.S. , Borovkova E.I. , Ishbulatov Y.M. , Gorshkov A.Y. , Korolev A.I. , Dadaeva V.A. , Fedorovich A.A. , Kuligin A.V. , Drapkina O.M. , Karavaev A.S. , Kiselev A.R.
Synchronization of autonomic control loops of blood circulation in patients with COVID-19
Russian Open Medical Journal. 2021. V.10. N3. DOI: 10.15275/rusomj.2021.0307 OpenAlex
Dates:
Submitted: Mar 17, 2021
Accepted: Jul 19, 2021
Identifiers:
OpenAlex: W3205327334
Citing:
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OpenAlex 9
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