Study of normal human serum proteomic profile under conditions of hyperbaric oxygen-nitrogen-argon exposure

Study of normal human serum proteomic profile under conditions of hyperbaric oxygen-nitrogen-argon exposure Full article

Journal

Bulletin of Experimental Biology and Medicine
ISSN: 0007-4888 , E-ISSN: 1573-8221

Output data

Year: 2010, Volume: 149, Number: 1, Pages: 37-39 Pages count : 3 DOI: 10.1007/s10517-010-0869-4

Tags

blood serum, hyperbaric exposure, proteomic profiling

Authors

Pakharukova N.A. ¹ , Pastushkova L.K. ¹ , Popova Y.A. ¹ , Trifonova O.P. ¹ , Larina I.M. ¹

Affiliations

1	Institute of Biomedical Problems, Russian Academy of Sciences

The dynamics of changes in serum proteome was studied under conditions of experimental 9-day seclusion in a pressure chamber at 5 m H2O pressure with modified gaseous environment. The proteomic profile for the molecular weight range of 1000-17,000 Da changed by 75%. Increased content of acute phase proteins (complement components, inter-α-trypsin inhibitor, and high-molecular-weight kininogen) was observed on day 1 of the experiment before the exposure. On day 9 of exposure, the peaks of AII, CI, and CII apolipoproteins decreased and angiotensin II peak increased.

Pakharukova N.A. , Pastushkova L.K. , Popova Y.A. , Trifonova O.P. , Larina I.M.
Study of normal human serum proteomic profile under conditions of hyperbaric oxygen-nitrogen-argon exposure
Bulletin of Experimental Biology and Medicine. 2010. V.149. N1. P.37-39. DOI: 10.1007/s10517-010-0869-4 OpenAlex

Пахарукова Н.А. , Пастушкова Л.Х. , Попова Ю.А. , Трифонова О.П. , Ларина И.М.
Исследование протеомного профиля сыворотки крови здорового человека в условиях гипербарической кислородно-азотно-аргоновой среды
Бюллетень экспериментальной биологии и медицины. 2010. Т.149. №1. С.42-44.

Submitted:

Jul 2, 2009

OpenAlex:

W1968294988

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