The “PHOENIX” Space Experiment: Study of Space Radiation Impact on Cells Genetic Apparatus on Board the International Space Station

The “PHOENIX” Space Experiment: Study of Space Radiation Impact on Cells Genetic Apparatus on Board the International Space Station Full article

Conference

1st International Symposium 'Physics, Engineering and Technologies for Bio-Medicine'
18-23 Oct 2016 , Москва

Journal

Journal of Physics: Conference Series
ISSN: 1742-6596 , E-ISSN: 1742-6588

Output data

Year: 2017, Volume: 784, Article number : 012024, Pages count : 6 DOI: 10.1088/1742-6596/784/1/012024

Tags

PHOENIX; Space Experiment; Space Radiation; Cells; Genetic Apparatus; International Space Station; DNA Fragmentation; Human Lymphocytes; Mouse Bone Marrow; Survival

Authors

Karganov M Yu ^1,2 , Alchinova I B ^1,2 , Yakovenko E N ^1,2 , Kushin V V ^3,4 , Inozemtsev K O ^3,4 , Strádi A ⁵ , Szabó J ⁵ , Shurshakov V A ⁴ , Tolochek R V ⁴

Affiliations

1	Research Institute for Space Medicine, Federal Biomedical Agency of Russia, Orekhoviy boulevard, 28, Moscow, 115682, Russian Federation
2	The Institute of General Pathology and Pathophysiology, Baltiyskaya str., 8, Moscow, 125315, Russian Federation
3	National Research Nuclear University MEPhI (Moscow Engineering Physics Institute), Kashirskoye shosse, 31, Moscow, 115409, Russian Federation
4	Russian Academy of Sciences, Institute of Biomedical Problems, Khoroshevskoye shosse, 76A, Moscow, 123007, Russian Federation
5	Hungarian Academy of Sciences, Centre for Energy Research (MTA EK), P. O. B. 49, H-1525, Budapest, Hungary

The preliminary results of the 1st session of Russian "PHOENIX" long-term space experiment are presented. The survival of dried human lymphocytes and mouse bone marrow cells in 199 days space flight is studied. The degree of DNA fragmentation is analysed for samples flown in different ISS compartments. It is shown that biological data correlates with the results of space radiation dose measurements.

Karganov M.Y. , Alchinova I.B. , Yakovenko E.N. , Kushin V.V. , Inozemtsev K.O. , Strádi A. , Szabó J. , Shurshakov V.A. , Tolochek R.V.
The “PHOENIX” Space Experiment: Study of Space Radiation Impact on Cells Genetic Apparatus on Board the International Space Station
Journal of Physics: Conference Series. 2017. V.784. 012024 :1-6. DOI: 10.1088/1742-6596/784/1/012024 WOS Scopus РИНЦ OpenAlex

Published print:	Jan 25, 2017
Published online:	Jan 25, 2017

Web of science:	WOS:000399813000024
Scopus:	2-s2.0-85013113200
Elibrary:	28333935
OpenAlex:	W2581744646

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