Abstract: The previous results of a wide research program in the conditions of ground-based models reproducing space flight factors on Earth formed built the basis for the formation of the concept of hypogravity motor syndrome, including changes in all departments of the musculoskeletal system. One of the most frequently observed phenomena during the transition to weightlessness is back pain, which is also recorded in test participantsthe subjects under conditions of "dDry" iImmersion (DI). The exact mechanisms of back pain caused by microgravity remain unknown. In previous studies in conditions of "dDry" iImmersion it was shown that support withdrawal is accompanied by the development of changes in transverse stiffness and leads to initial signs of atrophy of the back extensor muscles of the back, as well as changes in the architecture of the spine (changes in curvature of the spine, an increase in the size height of intervertebral discs, an increase in the total length of the spine), which isare accompanied by the development of backpain symptoms. The results of the conducted studies suggest the time frame of the acute period of adaptation in conditions of deep motor unloading. Despite the constancy of the earth's gravitational load, however, the adaptive capabilities in the population vary, and the changes in the spine observed in simulated microgravity may be important for describing the possibilities of functional adaptation of the musculoskeletal system to both unloading and loading conditions under natural "household" stress. It can help to form the basis for describing the causes of the formation of a number of pathological processes as a result of the exhaustion of the potential for functional adaptation. The study is supported by the Russian Science Foundation, project № 25-25-00366, https://rscf.ru/project/25-25-00366/

Cite: Rukavishnikov I. , Markova A. , Glagoleva S. , Shigueva T. , Tomilovskaya E.
Hypogravitational changes of the human spinal column in conditions of deep motor unloading
44 Annual the International Society of Gravitational Physiology Meeting (ISGP), Sapporo, 2025 18-23 May 2025