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Altered Sensitivity to UV Light and Radiation in Bacillus Bacteria Exposed to a Hypomagnetic Field Научная публикация

Журнал Microbiology
ISSN: 1608-3237 , E-ISSN: 0026-2617
Вых. Данные Год: 2025, Том: 94, Номер: 5, Страницы: 707-714 Страниц : 7
Ключевые слова hypomagnetic field, biomagnetic effects, B. subtilis, DNA repair genes, oxidative stress response
Авторы Fialkina S.V. 1,2 , Osipova P.J. 1 , Lebedev V.M. 3 , Spassky A.V. 3 , Yurov D.S. 3 , Poddubko S.V. 1 , Orlov O.I. 1
Организации
1 ГНЦ РФ - ИМБП РАН
2 Gamaleya National Research Center for Epidemiology and Microbiology, Ministry of Health of the Russian Federation, Moscow, 123098 Russia
3 Skobeltsyn Research Institute of Nuclear Physics, Moscow State University, Moscow, 119991 Russia

Информация о финансировании (1)

1 Министерство науки и высшего образования Российской Федерации FMFR-2024-0042

Реферат: This study assessed the modulating effect of hypomagnetic field (HMF) on bacterial cells exposed to ultraviolet light or radiation. After exposure to physical stressors, bacterial spores were allowed to recover in a hypomagnetic chamber that attenuates the Earth’s magnetic field by almost 1000 times. The cells that recovered under HMF conditions after exposure to UV light or radiation demonstrated increased survival and formed larger colonies on nutrient medium. That is, under hypomagnetic conditions, bacterial populations had higher rates of growth and proliferation. At the molecular level, enhanced expression was observed for a range of genes involved in DNA repair and response to oxidative stress, which could ensure more efficient repair of damage accumulated in bacterial cells after exposure to pulsed UV light or radiation. Genes of the non-homologous end joining (NHEJ) and base excision repair (BER) systems, as well as the antioxidant enzyme catalase, were activated under HMF conditions, while the expression of genes involved in the SOS response was decreased. Although HMF itself had no obvious effect on the viability of bacterial cells, it clearly enhanced their ability to recover from exposure to UV or radiation. These results indicate that hypomagnetic field acts as a modulator of stress response in microorganisms, which is important for understanding the possibility of their survival and adaptation in the extreme conditions of outer space.
Библиографическая ссылка: Fialkina S.V. , Osipova P.J. , Lebedev V.M. , Spassky A.V. , Yurov D.S. , Poddubko S.V. , Orlov O.I.
Altered Sensitivity to UV Light and Radiation in Bacillus Bacteria Exposed to a Hypomagnetic Field
Microbiology. 2025. Т.94. №5. С.707-714.
Оригинальная: Фиалкина С.В. , Осипова П.Д. , Лебедев В.М. , Спасский А.В. , Юров Д.С. , Поддубко С.В. , Орлов О.И.
ИЗМЕНЕНИЕ ЧУВСТВИТЕЛЬНОСТИ К УЛЬТРАФИОЛЕТУ И РАДИАЦИИ МИКРООРГАНИЗМОВ РОДА BACILLUS В УСЛОВИЯХ ГИПОМАГНИТНОГО ПОЛЯ
Микробиология. 2025. Т.94. №5. С.437-446. DOI: 10.7868/S3034546425050076
Даты:
Поступила в редакцию: 15 мая 2025 г.
Принята к публикации: 29 мая 2025 г.
Идентификаторы БД: Нет идентификаторов
Цитирование в БД: Пока нет цитирований