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Dry Immersion as a Ground-Based Model of Microgravity Physiological Effects Обзор

Журнал Frontiers in Physiology
ISSN: 1664-042X
Вых. Данные Год: 2019, Том: 10, Номер: 284, DOI: 10.3389/fphys.2019.00284
Ключевые слова dry immersion, motor control, gravity unloading, support withdrawal, supportlessness
Авторы Tomilovskaya Elena 1 , Shigueva Tatiana 1 , Sayenko Dimitry 2 , Rukavishnikov Ilya 1 , Kozlovskaya Inessa 1
Организации
1 RF SSC – Institute of Biomedical Problems, Russian Academy of Sciences, Russia
2 Center for Neuroregeneration, Houston Methodist Research Institute, United States

Информация о финансировании (1)

1 Министерство науки и высшего образования Российской Федерации 63.1

Реферат: Dry immersion (DI) is one of the most widely used ground models of microgravity. DI accurately and rapidly reproduces most of physiological effects of short-term space flights. The model simulates such factors of space flight as lack of support, mechanical and axial unloading as well as physical inactivity. The current manuscript gathers the results of physiological studies performed from the time of the model’s development. This review describes the changes induced by DI of different duration (from few hours to 56 days) in the neuromuscular, sensory-motor, cardiorespiratory, digestive and excretory, and immune systems, as well as in the metabolism and hemodynamics. DI reproduces practically the full spectrum of changes in the body systems during the exposure to microgravity. The numerous publications from Russian researchers, which until present were mostly inaccessible for scientists from other countries are summarized in this work. These data demonstrated and validated DI as a ground-based model for simulation of physiological effects of weightlessness. The magnitude and rate of physiological changes during DI makes this method advantageous as compared with other ground-based microgravity models. The actual and potential uses of the model are discussed in the context of fundamental studies and applications for Earth medicine.
Библиографическая ссылка: Tomilovskaya E. , Shigueva T. , Sayenko D. , Rukavishnikov I. , Kozlovskaya I.
Dry Immersion as a Ground-Based Model of Microgravity Physiological Effects
Frontiers in Physiology. 2019. V.10. N284. DOI: 10.3389/fphys.2019.00284 WOS Scopus РИНЦ PMID PMCID OpenAlex
Даты:
Поступила в редакцию: 21 апр. 2018 г.
Принята к публикации: 4 мар. 2019 г.
Идентификаторы БД:
Web of science: WOS:000462577400001
Scopus: 2-s2.0-85066454012
РИНЦ: 41649138
PMID (PubMed): 30971938
PMCID (PubMed Central): PMC6446883
OpenAlex: W2922581404
Цитирование в БД:
БД Цитирований
Scopus 137
OpenAlex 138
Альметрики: