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The effect of five-day dry immersion on the nervous and metabolic mechanisms of the circulatory system Научная публикация

Журнал Frontiers in Physiology
ISSN: 1664-042X
Вых. Данные Год: 2020, Номер: 11, Номер статьи : 692, Страниц : DOI: 10.3389/fphys.2020.00692
Авторы Русанов Василий Борисович 1 , Пастушкова Людмила Ханифовна 1 , Ларина Ирина Михайловна 1 , Черникова Анна Григорьевна 1 , Гончарова Анна Георгиевна 1 , Носовский Андрей Максимович 1 , Каширина Дарья Николаевна 1 , Бржозовский Александр Геннадьевич 1,2 , Navasiolava N. 3 , Кононихин Алексей Сергеевич 2,4 , Куссмауль Анна Рейнгольдовна 1 , Custaud M.A. 3 , Nikolaev E.N. 2
Организации
1 IBMP RAS
2 Skolkovo Institute of Science and Technology, Skolkovo, Russia
3 University of Angers, Angers, France
4 V.L. Talrose Institute for Energy Problems of Chemical Physics, N.N. Semenov Federal Center of Chemical Physics, Russian Academy of Sciences, Moscow, Russia

Реферат: The purpose of the study was to investigate the regulatory and metabolic changes in the circulatory system when simulating microgravity conditions in a five-day dry immersion. These changes reflect the adaptation processes characteristic for the initial stages of a space flight or a short-duration space flight. Studies were conducted with 13 healthy male volunteers aged 21 to 29 years. The assessment of regulatory and metabolic processes in the circulatory system was based on the heart rate variability (HRV) and urine proteomic profile analysis. It was found that the restructuring of hemodynamics during 5 days hypogravity begins with the inclusion of the nervous circuit of regulation, and for manifestations at the body fluids protein composition level and activation of the metabolic regulation, these periods are apparently insufficient. Perhaps this is due to the fact that the metabolic regulation, being evolutionarily ancient and genetically determined, is more stable and requires more time for its pronounced activation when stimulated by extreme life conditions.
Библиографическая ссылка: Rusanov V.B. , Pastushkova L.K. , Larina I.M. , Chernikova A.G. , Goncharova A.G. , Nosovskii A.M. , Kashirina D.N. , Brzhozovskii A.G. , Navasiolava N. , Kononikhin A.S. , Kussmaulʹ A.R. , Custaud M.A. , Nikolaev E.N.
The effect of five-day dry immersion on the nervous and metabolic mechanisms of the circulatory system
Frontiers in Physiology. 2020. N11. 692 . DOI: 10.3389/fphys.2020.00692 WOS Scopus РИНЦ PMID PMCID OpenAlex
Идентификаторы БД:
Web of science: WOS:000555792700001
Scopus: 2-s2.0-85088501893
РИНЦ: 45415431
PMID (PubMed): 32754043
PMCID (PubMed Central): PMC7366513
OpenAlex: W3040780224
Цитирование в БД:
БД Цитирований
Scopus 9
OpenAlex 9
Альметрики: