Weightlessness leads to an increase granulosa cells in the growing follicle | Sciact

Weightlessness leads to an increase granulosa cells in the growing follicle Научная публикация

Журнал

npj Microgravity
ISSN: 2373-8065

Вых. Данные

Год: 2024, Том: 10, Номер: 1, DOI: 10.1038/s41526-024-00413-4

Авторы

Kikina Anna Yu. ¹ , Matrosova Mariia S. ^2,3 , Gorbacheva Elena Yu. ^4,5 , Gogichaeva Ksenia K. ⁴ , Toniyan Konstantin A. ^4,5 , Boyarintsev Valery V. ⁶ , Kotov Oleg V. ⁴ , Ogneva Irina V. ^4,7

Организации

1	Gagarin Research and Test Cosmonaut Training Center, 141160, Star City, Moscow Region, Russia
2	Radiology Department, European Medical Center, 129090, Moscow, Russia
3	Research Center of Neurology, 125367 Moscow, Russia.
4	Cell Biophysics Lab, State Scientific Center of the Russian Federation Institute of Biomedical Problems of the Russian Academy of Sciences, 123007, Moscow, Russia
5	Gynecology Department, FGBU KB1 (Volynskaya) UDP RF, 121352 Moscow, Russia
6	Emergency and Extreme Medicine Department, Central State Medical Academy UDP RF, 121359, Moscow, Russia
7	Medical and Biological Physics Department, I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia

Информация о финансировании (1)

Министерство науки и высшего образования Российской Федерации

FMFR-2024-0041

The participation of women in space programs of increasing flight duration requires research of their reproductive system from the perspective of subsequent childbearing and healthy aging. For the first time, we present hormonal and structural data on the dynamics of recovery after a 157-day space flight in a woman of reproductive age. There were no clinically significant changes in the reproductive system, but detailed analysis shows that weightlessness leads to an increase in the proportion of early antral follicles and granulosa cells in large antral follicles. Returning to Earth’s gravity reduces the number and diameter of early antral follicles.

Kikina A.Y. , Matrosova M.S. , Gorbacheva E.Y. , Gogichaeva K.K. , Toniyan K.A. , Boyarintsev V.V. , Kotov O.V. , Ogneva I.V.
Weightlessness leads to an increase granulosa cells in the growing follicle
npj Microgravity. 2024. V.10. N1. DOI: 10.1038/s41526-024-00413-4 WOS Scopus РИНЦ PMID PMCID OpenAlex

Web of science:	WOS:001251889900002
Scopus:	2-s2.0-85196665530
РИНЦ:	68290047
PMID (PubMed):	38909072
PMCID (PubMed Central):	PMC11193763
OpenAlex:	W4399916832

БД	Цитирований
OpenAlex	1